Optimal management of cytomegalovirus retinitis in patients with AIDS

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Optimal management of cytomegalovirus retinitis in patients with AIDS

Cytomegalovirus (CMV) retinitis is the most common cause of vision loss in patients with acquired immunodeficiency syndrome (AIDS). CMV retinitis afflicted 25% to 42% of AIDS patients in the pre-highly active antiretroviral therapy (HAART) era, with most vision loss due to macula-involving retinitis or retinal detachment. The introduction of HAART significantly decreased the incidence and sever...

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The management of cytomegalovirus retinitis in AIDS.

Cytomegalovirus (CMV) shares many properties with other members of the herpesvirus family it exhibits latency, reactivates under suitable conditions to cause human disease, and it is incurable. CMV is the primary opportunistic viral infection in the immunosuppressed person and gives rise to a wide spectrum of disease. CMV is a major cause ofmorbidity and mortality among patients with AIDS, and ...

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Cytomegalovirus retinitis in AIDS.

Cytomegalovirus retinitis is common in adults with AIDS but has been reported infrequently in children with perinatally acquired HIV infection. The cases are presented of two infants with vertically acquired HIV infection who developed disseminated cytomegalovirus infection and retinitis, and who posed difficult management issues.

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Cytomegalovirus retinitis in HIV/AIDS patients

UNLABELLED Human immunodeficiency virus (HIV) has the ability to affect any organ in the body. In 70% of HIV-infected patients ocular manifestations were observed, which in the vast majority reflect the systemic disease and may be the first sign of a disseminated infection. AIM The purpose of this paper is to determine the prevalence and the clinical aspects of cytomegalovirus retinitis in HI...

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Treatment of cytomegalovirus retinitis in AIDS patients with intravitreal ganciclovir.

BACKGROUND Cytomegalovirus (CMV) retinitis is the most common opportunistic ocular infection in AIDS patients, and frequently leads to blindness if untreated. Intravitreal ganciclovir proved to be effective in stopping the progression of the disease. OBJECTIVES To determine the efficacy and complications of intravitreal ganciclovir (2 mg in 0.1 ml per injection) to control CMV retinitis. ST...

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ژورنال

عنوان ژورنال: Clinical Ophthalmology

سال: 2010

ISSN: 1177-5483

DOI: 10.2147/opth.s6700